HTS10307
HTS10307 is a small-molecule inhibitor of the AP1 transcription factor ΔFOSB. It inhibits the binding of ΔFOSB with JUND and DNA, with IC50 values of approximately ~3 μM and ~7 μM, respectively. HTS10307 serves as a chemical probe for investigating the role of ΔFOSB in pathological conditions such as drug addiction, Alzheimer's disease, and Parkinson's disease.
Product Specifications
CAS Number
81682-91-9
Smiles
N#CC=1C (=O) NC (=CC1C=2OC=CC2) C=3SC=CC3
Molecular Formula
C14H8N2O2S
Molecular Weight
268.29
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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