13-O-Desmethyl tacrolimus
13-O-Desmethyl tacrolimus (13-DMT; 13-O-Demethyl FK 506) is the primary metabolite of Tacrolimus. It exhibits weaker immunosuppressive activity compared to Tacrolimus. This compound is primarily utilized in monitoring studies of Tacrolimus through the analysis of the 13-DMT/Tacrolimus ratio.
Product Specifications
CAS Number
139958-51-3
Smiles
O (C) [C@@H]1[C@]2 (O[C@@] (O) (C (=O) C (=O) N3[C@] (C (=O) O[C@H] (\C (=C\[C@H]4C[C@@H] (OC) [C@H] (O) CC4) \C) [C@H] (C) [C@@H] (O) CC (=O) [C@H] (CC=C) /C=C (\C) /C[C@H] (C) C1) (CCCC3) [H]) [C@H] (C) C[C@@H]2O) [H]
Molecular Formula
C43H67NO12
Molecular Weight
790
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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