NOD1/2 antagonist-2
NOD1/2 antagonist-2 (Compound 26BH) is a dual NOD1/NOD2 antagonist with IC50 values of 2.36 μM for NOD1 and 4.16 μM for NOD2. It inhibits the NF-κB and MAPK inflammatory signaling pathways, thereby enhancing the effect of Paclitaxel in inhibiting the growth of Lewis lung cancer.
Product Specifications
CAS Number
2101736-25-6
Smiles
O=C1C=2C (=CC (NC (COCC3=CC=CC=C3) =O) =C (OC4=CC (N (C) C) =CC=C4) C2) NC (=O) [C@@H] (CCC (NCCC) =O) N1
Molecular Formula
C32H37N5O6
Molecular Weight
587.68
Storage Conditions
-20°C
Notes
For research use only.
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