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NOD1/2 antagonist-2

NOD1/2 antagonist-2 (Compound 26BH) is a dual NOD1/NOD2 antagonist with IC50 values of 2.36 μM for NOD1 and 4.16 μM for NOD2. It inhibits the NF-κB and MAPK inflammatory signaling pathways, thereby enhancing the effect of Paclitaxel in inhibiting the growth of Lewis lung cancer.

Product Specifications

CAS Number

2101736-25-6

Smiles

O=C1C=2C (=CC (NC (COCC3=CC=CC=C3) =O) =C (OC4=CC (N (C) C) =CC=C4) C2) NC (=O) [C@@H] (CCC (NCCC) =O) N1

Molecular Formula

C32H37N5O6

Molecular Weight

587.68

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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