CPAG-1
CPAG-1 is a small molecule activator of the progesterone receptor membrane component 2 (PGRMC2) . It facilitates the delivery of mitochondrially-produced heme to the nucleus via PGRMC2 and activates thermogenesis-related genes like Ucp1 and Pgc-1α in brown adipose tissue (BAT), while reducing lipid accumulation in BAT. Additionally, CPAG-1 lowers fasting blood glucose and insulin levels, improving glucose tolerance and insulin sensitivity. It is applicable for research in type 2 diabetes.
Product Specifications
CAS Number
2094991-62-3
Smiles
N (C ([C@@H] (NC (CCC) =O) CC (C) C) =O) C1=CC2=C (C=C1) C=CC=C2
Molecular Formula
C20H26N2O2
Molecular Weight
326.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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