Sunitinib glucuronate
Sunitinib (SU 11248) glucuronate is a multi-target receptor tyrosine kinase inhibitor with IC50 values of 80 nM for VEGFR2 and 2 nM for PDGFRβ. As an ATP-competitive inhibitor, it effectively suppresses Ire1α phosphorylation by inhibiting autophosphorylation and subsequent RNase activation.
Product Specifications
CAS Number
1818285-48-1
Smiles
[C@H] ([C@@H] ([C@H] (C=O) O) O) ([C@@H] (C (O) =O) O) O.C (=C\1/C=2C (NC1=O) =CC=C (F) C2) \C3=C (C) C (C (NCCN (CC) CC) =O) =C (C) N3
Molecular Formula
C28H37FN4O9
Molecular Weight
592.62
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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