Sirtuin-IN-1
Sirtuin-IN-1 (Compound 18) is an inhibitor of SIRT1/2, with IC50 values of 6.2 μM for SIRT1 and 4.2 μM for SIRT2. It can induce G1 phase cell cycle arrest and demonstrates effective anticancer activity against glioma.
Product Specifications
CAS Number
1392810-44-4
Smiles
N#CC1=CC=CC (=C1) NC (=O) NC2C3=CC (=CC=C3OC (C) (C) C2) NC (=O) OC (C) (C) C
Molecular Formula
C24H28N4O4
Molecular Weight
436.51
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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