C-Kit-IN-14
C-Kit-IN-14 (Compound 1) is a c-kit kinase inhibitor. It effectively inhibits the phosphorylation of wild-type c-kit, with an IC50 value of 0.4 nM for pKIT. Additionally, c-Kit-IN-14 inhibits Exon 11 KIT with an IC50 value of 0.4 nM. This compound is applicable in the research of mast cell-mediated diseases, such as urticaria.
Product Specifications
CAS Number
3041025-49-1
Smiles
C (NC1=CC (=C (F) C=C1Cl) C2=NN (N=N2) C3CC3) (=O) C4=C5N (C=CC (=C5) C6=CN (C[C@H] (COC) O) N=C6C) N=C4
Molecular Formula
C26H25ClFN9O3
Molecular Weight
565.99
Storage Conditions
-20°C
Notes
For research use only.
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