Cis-V-11-0711
Cis-V-11-0711 is the cis form of V-11-0711, a potent and selective inhibitor of Chk-α with an IC50 of 20 nM. V-11-0711 significantly reduces PCho levels and can cause reversible growth arrest. At high concentrations, V-11-0711 induces apoptosis and is applicable in research on cervical cancer and triple-negative breast cancer.
Product Specifications
CAS Number
1428338-79-7
Smiles
[C@@] (CCC1=C (OC2CCOCC2) C=CC=C1) (O) ([C@@]3 (C4CCN (C3) CC4) [H]) C5=CC=CC=C5
Molecular Formula
C27H35NO3
Molecular Weight
421.58
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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