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DIM-3,5-Cl2

DIM-3,5-Cl2 is an inverse agonist of NR4A1/NR4A2 that can downregulate pro-carcinogenic responses or gene products regulated by these receptors. It induces the production of reactive oxygen species (ROS), malondialdehyde, and lipid peroxides, while decreasing the expression of GPX4 and SLC7A11 and increasing CD71 expression. Additionally, DIM-3,5-Cl2 can induce ferroptosis and is applicable in research on triple-negative breast cancer.

Product Specifications

CAS Number

2595179-74-9

Smiles

ClC=1C=C (Cl) C=C (C1) C (C2=CNC=3C=CC=CC32) C4=CNC=5C=CC=CC54

Molecular Formula

C23H16Cl2N2

Molecular Weight

391.3

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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