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RYL-634

RYL-634 is a potent broad-spectrum antiviral agent. It exerts its antiviral effects by inhibiting the activity of human dihydroorotate dehydrogenase (HsDHODH), thereby blocking the pyrimidine supply necessary for viral replication. RYL-634 demonstrates significant inhibitory action against various viruses, with EC50 values of 7 nM for DENV, 20 nM for ZIKV, 4 nM for EV71, 5 nM for HCV, and 13 nM for HIV. This compound can be used for research into diseases associated with multiple viral infections.

Product Specifications

CAS Number

2187352-99-2

Smiles

O=C1C=2C (F) =CC=CC2NC (C=3C=CC (OC4=CC=C (C=C4) N (CC) CC) =C (F) C3) =C1C

Molecular Formula

C26H24F2N2O2

Molecular Weight

434.49

Storage Conditions

-20°C

Notes

For research use only.

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