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MFDCH016

MFDCH016 is a potent inhibitor of HDAC1/6 (IC50= 38/59 nM) and CDK4/6 (IC50= 680/720 nM) . It induces apoptosis in MCF-7 cells and causes cell cycle arrest in the G2/M and G0/G1 phases. MFDCH016 modulates the HDAC-p21-CDK signaling pathway, increasing levels of acetylated H3 and p21, making it useful for breast cancer research.

Product Specifications

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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