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MyD88-IN-4

MyD88-IN-4 is a MyD88 inhibitor. It exerts antiviral effects by upregulating IFN-β and demonstrates anti-inflammatory properties by inhibiting the production of pro-inflammatory cytokines. MyD88-IN-4 prevents the formation of MyD88 homodimers and interferes with its interaction with IRF3/IRF7. In a mouse model infected with VEEV TC-83, MyD88-IN-4 shows efficacy against encephalitic alphavirus infections by reducing viral replication and increasing survival rates. This compound is applicable for research on alphavirus infections, bacterial toxin-related diseases, and sepsis.

Product Specifications

CAS Number

1801552-15-7

Smiles

N ([C@H] (C (=O) N1CCCC1) C (C) C) (C (=O) [C@@H]2CC[C@@H] (C (N ([C@H] (C (=O) N3CCCC3) C (C) C) CCCC4=CC=CC=C4) =O) CC2) CCCC5=CC=CC=C5

Molecular Formula

C44H64N4O4

Molecular Weight

713.02

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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