Antifungal agent 137
Antifungalagent 137 (Compound 4S) is an antifungal compound that inhibits Phomopsis sp. (PS) with an EC50 value of 0.15 μg/mL. It targets lanosterol 14α-demethylase (CYP51) with an IC50 value of 5.00 μg/mL. Additionally, it disrupts PS mycelial morphology, compromises cell membrane integrity, and increases intracellular ROS levels, inducing oxidative stress. This compound is useful for research on fungal infections.
Product Specifications
CAS Number
3032062-22-6
Smiles
O=S (=O) (C1=CC (F) =CC=C1F) N2CCN (CC2) CC (O) (C3=CC=C (F) C=C3F) CN4N=CN=C4
Molecular Formula
C21H21F4N5O3S
Molecular Weight
499.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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