P-gp inhibitor 30

P-gp inhibitor 30 is a potent P-gp inhibitor that can reverse multidrug resistance in breast cancer, rendering resistant cells sensitive to Doxorubicin (ADM) . When used in combination with ADM, P-gp inhibitor 30 facilitates apoptosis and induces autophagy in resistant breast cancer cells, while also inhibiting cell proliferation, migration, and invasion. This inhibitor effectively suppresses tumor growth both in vitro and in vivo, making it valuable for research on drug-resistant breast cancer.