JNJ627
JNJ627 is a small molecule allosteric inhibitor of IL-17A with a KD value of 92 nM. It effectively inhibits the binding of IL-17A to IL-17RA, with an IC50 of 16 nM. JNJ627 also suppresses the secretion of granulocyte colony-stimulating factor stimulated by IL-17A. This compound is applicable in research on autoimmune diseases (e.g., psoriasis) .
Product Specifications
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC402617-100 1x 100 µL
Cadherin 17 / LI Cadherin (Liver-Intestine Marker) (CDH17/2617), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC882099-100 1x 100 µL
Catenin, beta (p120) (CTNNB1/2099), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC743732-100 1x 100 µL
Tubulin beta 3 / TUBB3 (Neuronal & Stem Cell Marker) (TUBB3/3732), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC042316-500 1x 500 µL
Cdk2 / p34cdc2 Serine-Threonine Kinase (AN4.3), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC402055-100 1x 100 µL
Carcinoembryonic Antigen (CEA) / CD66 (C66/2055R), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 