Mc-Lys (PEG12) -Cap-Ala-Ala-PABC-exatecan
Mc-Lys (PEG12) -Cap-Ala-Ala-PABC-exatecan (compound 12) is a drug-linker conjugate used in antibody-drug conjugates (ADCs) . It comprises an ADC linker [Mc-Lys (PEG12) -Cap-Ala-Ala-PABC] and the DNA topoisomerase I inhibitor Exatecan. This compound is applicable for developing ADCs targeting HER2-positive breast cancer.
Product Specifications
CAS Number
3067680-81-0
Smiles
N (C (OCC1=CC=C (NC ([C@@H] (NC ([C@@H] (NC (CCCCCNC ([C@@H] (NC (CCCCCN2C (=O) C=CC2=O) =O) CCCCNC (CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC) =O) =O) =O) C) =O) C) =O) C=C1) =O) [C@@H]3C4=C5C (C=6N (C5) C (=O) C7=C (C6) [C@] (CC) (O) C (=O) OC7) =NC=8C4=C (CC3) C (C) =C (F) C8
Molecular Formula
C86H123FN10O26
Molecular Weight
1731.97
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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