YAP/TEAD-IN-2-1
YAP/TEAD-IN-2 (Compound T-1) is an inhibitor of YAP/TEAD. This compound suppresses luciferase activity driven by YAP/TEAD in 293T cells and exhibits strong antiproliferative effects on human pleural mesothelioma NCI-H226 cells. YAP/TEAD-IN-2 is applicable for studying diseases associated with disruptions in the Hippo pathway, particularly cancer.
Product Specifications
CAS Number
2957895-40-6
Smiles
O=C (N) C1=NN=C (O1) C=2C=NN3C (=O) C=C (NC23) C=4C=CC (=CC4) C5CCCCC5
Molecular Formula
C21H20N6O3
Molecular Weight
404.43
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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