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YAP/TEAD-IN-2-1

YAP/TEAD-IN-2 (Compound T-1) is an inhibitor of YAP/TEAD. This compound suppresses luciferase activity driven by YAP/TEAD in 293T cells and exhibits strong antiproliferative effects on human pleural mesothelioma NCI-H226 cells. YAP/TEAD-IN-2 is applicable for studying diseases associated with disruptions in the Hippo pathway, particularly cancer.

Product Specifications

CAS Number

2957895-40-6

Smiles

O=C (N) C1=NN=C (O1) C=2C=NN3C (=O) C=C (NC23) C=4C=CC (=CC4) C5CCCCC5

Molecular Formula

C21H20N6O3

Molecular Weight

404.43

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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