MAO-B-IN-49
MAO-B-IN-49 is a selective, reversible MAO-B inhibitor with an IC50 of 1 nM for human MAO-B. It demonstrates significantly higher selectivity for MAO-B over MAO-A (IC50 = 633.9 nM) . MAO-B-IN-49 reduces lipopolysaccharide (LPS) -induced ROS production in HT22 cells. It possesses notable neuroprotective properties and significantly improves motor dysfunction in MPTP-induced Parkinson's disease (PD) mouse models. MAO-B-IN-49 is applicable for Parkinson's disease research.
Product Specifications
CAS Number
3098883-91-8
Smiles
[C@@H] (C (N) =O) (C) N1CC=2C (=CC (OCC3=CC (F) =C (F) C=C3) =CC2) OCC1
Molecular Formula
C19H20F2N2O3
Molecular Weight
362.38
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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