SQS-IN-1

SQS-IN-1 is an inhibitor of squalene synthase (SQS) . It exhibits potent and broad-spectrum antiproliferative effects on various murine and human lung cancer cell lines. SQS-IN-1 impedes DNA replication and cell cycle progression, resulting in mitochondrial hyperpolarization and inducing apoptosis. Additionally, it hinders cell migration and invasion. SQS-IN-1 is applicable in lung cancer research.