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ML-93

ML-93 is an orally active SAE inhibitor with an IC50 value of 0.4 μM. It effectively inhibits the SUMOylation pathway in HCT116 cells and demonstrates potent antitumor activity in HCT116 colorectal cancer xenograft models. ML-93 is applicable in colorectal cancer research.

Product Specifications

CAS Number

1858275-91-8

Smiles

CC1=C ([C@H]2C=3C (CCO2) =CC=C (Cl) C3) C=C (C (=O) C=4C (N[C@@H]5C[C@H] (COS (N) (=O) =O) [C@@H] (O) C5) =NC=NC4) S1

Molecular Formula

C25H27ClN4O6S2

Molecular Weight

579.08

Storage Conditions

-20°C

Notes

For research use only.

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