HM12
HM12 is a covalent inhibitor of L-/T-type calcium channels. This compound effectively suppresses Cav1.2 (L-type) and Cav3.2 (T-type) calcium channels, while showing selectivity for N-type channels. The inhibitory effect produced by HM12 is irreversible and persists even after elution. HM12 is applicable in research related to hypertension, pain, epilepsy, and other conditions.
Product Specifications
CAS Number
2376051-91-9
Smiles
O=C (OCCOC (=O) C1=C (NC2=C (C (=O) C (C) (C) CC2) C1C=3C=C (Br) C=C (Br) C3O) C) C (=C) C
Molecular Formula
C25H27Br2NO6
Molecular Weight
597.3
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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