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HM12

HM12 is a covalent inhibitor of L-/T-type calcium channels. This compound effectively suppresses Cav1.2 (L-type) and Cav3.2 (T-type) calcium channels, while showing selectivity for N-type channels. The inhibitory effect produced by HM12 is irreversible and persists even after elution. HM12 is applicable in research related to hypertension, pain, epilepsy, and other conditions.

Product Specifications

CAS Number

2376051-91-9

Smiles

O=C (OCCOC (=O) C1=C (NC2=C (C (=O) C (C) (C) CC2) C1C=3C=C (Br) C=C (Br) C3O) C) C (=C) C

Molecular Formula

C25H27Br2NO6

Molecular Weight

597.3

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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