EGFR-IN-174

EGFR-IN-174 is a potent inhibitor of EGFR (IC50= 0.17 μM) and also effectively inhibits VEGFR-2 (IC50= 0.2007 μM) . It demonstrates strong anticancer properties with low toxicity towards normal cells. EGFR-IN-174 induces G2/M and Pre-G1 phase cell cycle arrest and significantly triggers apoptosis. It is employed in cancer research, including studies on colorectal cancer, hepatocellular carcinoma, and breast cancer.