IDO1-IN-30
IDO1-IN-30 (Compound (R) -100) is a potent and highly selective inhibitor of IDO1. It exhibits an IC50 value of 4.8 nM against IDO1 in SKOV3 cells. In HepG2 cells, at a concentration of 25 μM, IDO1-IN-30 does not display significant cytotoxicity. Additionally, it eliminates inhibition of CYP450 enzymes, including 3A4, 2C9, and 2D6. This compound is suitable for research related to cancer and inflammatory diseases.
Product Specifications
CAS Number
2581050-29-3
Smiles
[C@@H] (O) (C1=C (N=CC=2N1C=NC2) C3CC3) C4=CN (N=N4) C5=C (F) C=C (OC) C (F) =C5
Molecular Formula
C19H16F2N6O2
Molecular Weight
398.37
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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