Tubulin-IN-57

Tubulin-IN-57 is a tubulin inhibitor and a potent antiproliferative agent that suppresses colony formation, migration, and invasion of ovarian cancer cells. It disrupts tubulin polymerization, inducing G2/M phase arrest and apoptosis (apoptosis) in SKOV3 cells. In SKOV3 xenograft tumor models, Tubulin-IN-57 demonstrates significant antitumor activity without noticeable toxicity. It is applicable for ovarian cancer research.