PDM-631
PDM-631 is a selective and orally active inhibitor of PDE2A with the ability to penetrate the blood-brain barrier. It demonstrates potent inhibitory activity against recombinant PDE2A in humans and rats, with IC50 values of 1.5 nM and 4.2 nM, respectively. PDM-631 increases cGMP levels in the rat cerebral cortex and is suitable for research on schizophrenia and neurodegenerative diseases.
Product Specifications
CAS Number
2095312-08-4
Smiles
[C@@H] (CC1=CC=C (OC (F) (F) F) C=C1) (C) N2C3=C (C (=N2) C4CC4) C (=O) N=C (C) N3
Molecular Formula
C19H19F3N4O2
Molecular Weight
392.38
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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