VEGFR-2-IN-73

VEGFR-2-IN-73 is a potent and highly selective inhibitor of VEGFR-2, demonstrating significantly stronger inhibition (IC50 = 0.0787 μM) compared to its effect on EGFR (IC50 = 1.31 μM) . It exhibits strong antiproliferative activity across various cancer cell lines, induces cell cycle arrest at the G2/M and Pre-G1 phases, and significantly promotes apoptosis. This compound is applicable in cancer research, including studies on colorectal cancer, hepatocellular carcinoma, and breast cancer.