IDO1-IN-32
IDO1-IN-32 (Compound 45) is a potent and orally active IDO1 inhibitor with an IC50 of 10 pM. It exhibits significant antiproliferative activity against Hela cells. In CT26 and LCC xenograft mouse models, IDO1-IN-32 significantly suppresses tumor growth by activating antitumor immunity. This compound is useful for studying colon and breast cancers.
Product Specifications
CAS Number
2456309-77-4
Smiles
O=C (O) C1=CC=CN1C2=CC (Cl) =C (C (=C2) NC (=O) NC3=CC=C (Cl) C=C3F) N (CC (C) C) CC (C) C
Molecular Formula
C26H29Cl2FN4O3
Molecular Weight
535.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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