Nav1.7-IN-19
Nav1.7-IN-19 is a potent, selective, and orally active Nav1.7 inhibitor with an IC50 value of 0.49 μM. It shows high selectivity for Nav1.7, exhibiting 312-fold and 662-fold selectivity over Nav1.1 and Nav1.5, respectively, in the inactivated state. Nav1.7-IN-19 weakly inhibits the hERG potassium channel. Additionally, Nav1.7-IN-19 possesses analgesic properties, making it useful for neurological disorder research.
Product Specifications
CAS Number
3097995-73-5
Smiles
O=C (N) C (NCCCC1=CC (Cl) =CC=C1OC2=CC (F) =C (C=C2Br) S (=O) (=O) NC3=NOC=C3) C4CC4
Molecular Formula
C23H23BrClFN4O5S
Molecular Weight
601.87
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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