JAK1-IN-19
JAK1-IN-19 (Compound 18) is a potent JAK1 inhibitor with IC50 values of 0.02 nM for JAK1, 0.5 nM for JAK2, 91 nM for JAK3, and 0.2 nM for TYK2. It demonstrates a higher intrinsic clearance in both rats and humans. JAK1-IN-19 is applicable for research into atopic dermatitis and other autoimmune diseases.
Product Specifications
CAS Number
2169271-17-2
Smiles
C (#N) [C@@H]1[C@@H] (N2N=C (NC3=CC=C (C=C3) C4=CN (C) N=C4) C (C (N) =O) =C2) COCC1
Molecular Formula
C20H21N7O2
Molecular Weight
391.44
Storage Conditions
-20°C
Notes
For research use only.
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