Y502-2304
Y502-2304 is a c-MycG-quadruplex stabilizer that exhibits potent antiproliferative activity in multiple myeloma (MM) cells. It downregulates c-Myc mRNA and protein expression and induces apoptosis in MM cells, as characterized by increased γH2AX levels, elevated reactive oxygen species (ROS) production, and mitochondrial dysfunction. Additionally, Y502-2304 significantly inhibits tumor growth in xenograft MM models and is useful for studying multiple myeloma.
Product Specifications
CAS Number
741278-95-5
Smiles
O=C (OC) C=1SC=2N=CN3N=C (N=C3C2C1C) C=4C=CC (=CC4) N (=O) =O
Molecular Formula
C16H11N5O4S
Molecular Weight
369.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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