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IN04

IN04 is an inhibitor of leucine-rich repeat kinase 1 (LRRK1) . It fully hinders the binding of ATP to the human LRRK1 kinase domain, thereby suppressing its kinase activity. IN04 significantly reduces the bone resorption capability of osteoclasts, with an IC50 value of 5.72 μM, and is applicable in osteoporosis research.

Product Specifications

CAS Number

838816-57-2

Smiles

O=C (OC) C=1C=CC=C (C1) NC (=O) CSC2=NN=C (O2) C=3C=C (OC) C=C (OC) C3

Molecular Formula

C20H19N3O6S

Molecular Weight

429.45

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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