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ZA18

ZA18 is a selective TRPM2 channel inhibitor with an IC50 value of 6.2 μM. It effectively suppresses intracellular Ca2+ overload triggered by TRPM2 channel activation and significantly reduces H2O2-induced cell death in SH-SY5Y cells. ZA18 is applicable for research on ischemia-reperfusion injury, inflammation, or other neurodegenerative diseases.

Product Specifications

CAS Number

2696407-32-4

Smiles

O=C (C=1C=CC (=CC1) C=2C=CC=CC2) C3=C (N=C4N3C=5C=CC=CC5N4CCN (CC) CC) C

Molecular Formula

C29H30N4O

Molecular Weight

450.59

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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