BI-5756

BI-5756 is a compound that acts as a CETP inhibitor and cannabinoid receptor 1 (CB1) agonist. It significantly raises HDL-C levels while reducing LDL-C levels. BI-5756 also enhances the function of regulatory T cells and maintains T cell-mediated anti-tumor activity. Additionally, it directly inhibits tumor cell growth and increases the expression of MHC I, MHC II, and CD80 on tumor cells. In models of graft-versus-host disease, BI-5756 offers protective effects. This compound is applicable for research in the areas of tumors, graft-versus-host disease, and metabolic disorders.