TLR9 antagonist 1
TLR9 antagonist1 (Compound 38) is a selective TLR9 inhibitor with an IC50 of 0.1 nM for hTLR9, demonstrating superior antagonistic activity compared to hTLR2/4/5/7/8. This compound exacerbates disease symptoms in mouse models of systemic lupus erythematosus (SLE) and raises levels of anti-dsDNA and anti-Sm antibodies. TLR9 antagonist1 is applicable in research on inflammatory and immune diseases such as lupus and arthritis.
Product Specifications
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6149957-01 0.1 mL
STUB1 (STIP1 Homology and U box-containing Protein 1, E3 Ubiquitin-protein Ligase CHIP, Antigen NY-CO-7, CLL-associated Antigen KW-8, Carboxy Terminus of Hsp70-interacting Protein, CHIP, PP1131, HSPABP2, NY-CO-7, SDCCAG7, UBOX1) (FITC)
Sign In for Pricing
View Details MBS6149957-02 5x 0.1 mL
STUB1 (STIP1 Homology and U box-containing Protein 1, E3 Ubiquitin-protein Ligase CHIP, Antigen NY-CO-7, CLL-associated Antigen KW-8, Carboxy Terminus of Hsp70-interacting Protein, CHIP, PP1131, HSPABP2, NY-CO-7, SDCCAG7, UBOX1) (FITC)
Sign In for Pricing
View Details 