A2AAR antagonist 5
A2AAR antagonist 5 is a selective A2AAR antagonist that inhibits NECA-stimulated adenylyl cyclase activity in hA2AAR-expressing CHO cells, with an IC50 of 1863 nM. It also shows strong free radical scavenging activity, with an EC50 of 22.21 μM in the DPPH assay. Notably, A2AAR antagonist 5 exhibits significant neuroprotective effects in in vitro models of cerebral ischemia and is applicable for research in cerebral ischemia studies.
Product Specifications
Storage Conditions
-20°C
Notes
For research use only.
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