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ARRY-371797

ARRY-371797 is an orally bioactive and potent inhibitor of p38αMAPKBChE, with IC50 values of 0.13 μM for p38αMAPK, 12.0 μM for hBChE, and greater than 100 μM for hAChE. This compound shows potential for research in Alzheimer's disease.

Product Specifications

CAS Number

3077831-12-7

Smiles

O=C (NCCN (C) C) C1=CC2=NN (C=C2C=C1OC3=CC=C (F) C=C3F) CC (C) C

Molecular Formula

C22H26F2N4O2

Molecular Weight

416.47

Storage Conditions

-20°C

Notes

For research use only.

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