PNR-3-82
PNR-3-82 is a selective inhibitor of Endonuclease G (EndoG) with an IC50 of 0.61 μM, showing greater efficacy than its inhibition of DNase I. It does not inhibit five enzymes related to cell death: DNase II, RNase A, protease, lactate dehydrogenase, and superoxide dismutase 1. With cytoprotective properties, PNR-3-82 prevents cell death induced by cisplatin and docetaxel and can be utilized in cell damage research.
Product Specifications
CAS Number
1424353-64-9
Smiles
O=C1NC (=S) NC (=O) C1=CC2=CN (C (=O) C=3C=CC=4C=CC=CC4C3) C=5C=CC (OC) =CC25
Molecular Formula
C25H17N3O4S
Molecular Weight
455.49
Storage Conditions
-20°C
Notes
For research use only.
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