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HPK1-IN-62

HPK1-IN-62 is a selective, orally active inhibitor of HPK-1 with an IC50 of 1.22 nM. It significantly enhances selectivity for GLK (> 665-fold) and LCK (> 1095-fold) . HPK1-IN-62 boosts T cell activation and shows synergy with anti-mPD-1 therapy in inhibiting tumor growth in the MC38 tumor model. It is applicable for research in colon cancer and cancer immunotherapy.

Product Specifications

Storage Conditions

-20°C

Notes

For research use only.

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