Dual FXR/PPARδ agonist-2
Dual FXR/PPARδ agonist-2 is a dual agonist for FXR and PPARδ, derived from the hybridization of the FXR agonist GW-4064 and the PPARδ agonist GW-0742. It exhibits potent dual-target activity, with an EC50 of 12.28 nM for FXR activation and a 69% activation rate of PPARδ at a concentration of 100 nM. Additionally, dual FXR/PPARδ agonist-2 demonstrates antifibrotic effects in a mouse model of pulmonary fibrosis.
Product Specifications
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC682881-100 1x 100 µL
CD63 (Late Endosomes Marker) (LAMP3/2881), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
IRBAHUCERS3AP374120UL 1 Each
Rabbit Anti Human CERS3 Polyclonal Affinity Purified (PBS with 0.05% sodium azide and 50% glycerol, pH7.4) (Western Blot,ELISA)
Sign In for Pricing
View Details 