EGFR/VEGFR2-IN-6

EGFR/VEGFR2-IN-6 (Compound 3k) is a dual inhibitor targeting EGFR and VEGFR2, exhibiting IC50 values of 10.53 μM for EGFR and 3.37 μM for VEGFR2. It demonstrates significant antiproliferative activity against breast cancer cells and induces G0/G1 cell cycle arrest and apoptosis, particularly early apoptosis. EGFR/VEGFR2-IN-6 is applicable in cancer research.