MRGPRX4 modulator-3
MRGPRX4 modulator-3 (Compound 1C) is an allosteric negative modulator of MAS-related G-protein coupled receptor X4 (MRGPRX4) . It significantly inhibits the activation response induced by Nateglinide (an orthosteric agonist), with an IC50 of 337 nM. MRGPRX4 modulator-3 is applicable in studies related to chronic itching, particularly cholestatic pruritus, and pain.
Product Specifications
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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