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VASH1/2-IN-1

VASH1/2-IN-1 (LV87) is a potent epoxide-based covalent inhibitor targeting tubulin detyrosination. It selectively inhibits VASH1/2 enzymes, with IC50 values for VASH1 and VASH2 being 0.007 μM and 0.09 μM, respectively.

Product Specifications

CAS Number

2911542-75-9

Smiles

C (N[C@H] (C (NCCC1=CC=CC=C1) =O) CCCC (NO) =O) (=O) [C@@H]2[C@@H] (C (N[C@@H] (CC3=CC=C (OCC4=CC=CC=C4) C=C3) C (O) =O) =O) O2

Molecular Formula

C34H38N4O9

Molecular Weight

646.7

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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