Antileishmanial agent-35
Antileishmanial agent-35 (Compound 6) is an antileishmanial compound with an IC50 of 0.29 μM against the promastigotes of Leishmania amazonensis. It acts by disrupting the electron transport chain (where ubiquinone plays a role), markedly reducing mitochondrial membrane potential and ATP levels, and increasing reactive oxygen species (ROS) production. Antileishmanial agent-35 is applicable in the study of cutaneous leishmaniasis.
Product Specifications
CAS Number
100611-91-4
Smiles
O=C1C=C (C (=O) C=C1C) C2CCCCC2
Molecular Formula
C13H16O2
Molecular Weight
204.27
Storage Conditions
-20°C
Notes
For research use only.
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