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Hakin-1

Hakin-1 is an inhibitor of the E3 ubiquitin ligase Hakai. It effectively blocks both overall ubiquitination mediated by Hakai and the specific ubiquitination of E-cadherin, thereby inhibiting the process of epithelial-mesenchymal transition (EMT) . Hakin-1 can impede tumor progression and cancer metastasis and is utilized for research in colorectal cancer and other cancers.

Product Specifications

CAS Number

346660-34-2

Smiles

O=C (O) C1=CC=C (C=C1) N2N=NN=C2SCC (=O) C3=CC=C (C=C3) N (=O) =O

Molecular Formula

C16H11N5O5S

Molecular Weight

385.35

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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