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APJ antagonist-1

APJ antagonist-1 is an apelin receptor (APJ) antagonist with potent β-arrestin inhibitory activity, exhibiting an IC50 of 3.1 μM. It selectively inhibits cancer cells overexpressing APJ and suppresses apelin-induced endothelial cell migration. The compound demonstrates high metabolic stability and is applicable in research on ovarian cancer and tumor angiogenesis.

Product Specifications

Storage Conditions

-20°C

Notes

For research use only.

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