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Kindlin 2 Mouse Monoclonal Antibody [A10G12]

Selected Variant

HA601343

Size: 100 µL

Fermitin family homolog 2 (FERMT2) also known as pleckstrin homology domain-containing family C member 1 (PLEKHC1) or kindlin-2 is a protein that in humans is encoded by the FERMT2 gene. Kindlin-2 is the first of the kindlin protein to be discovered in 1994. It was detected in a screen for epidermal growth factor (EGF)-induced mRNAs and initially named mitogen-inducible gene 2 (Mig-2) protein. FERMT2 is a component of extracellular matrix structures in mammalian cells and is required for proper control of cell shape change. A major task of kindlins is to regulate the activation of integrins. FERMT2 has been shown to interact with FBLIM1.

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

FLJ34213 antibody FLJ44462 antibody UNC112 antibody FERM2_HUMAN antibody Fermitin family homolog 2 antibody Fermt2 antibody KIND2 antibody Kindlin-2 antibody MIG-2 antibody MIG2 antibody Mitogen-inducible gene 2 protein antibody PH domain-containing family C member 1 antibody Pleckstrin homology domain containing family C (with FERM domain) member 1 antibody Pleckstrin homology domain-containing family C member 1 antibody PLEKHC1 antibody UNC112B antibody

Abbreviation

FERMT2, KIND2, MIG2, PLEKHC1

Swiss Prot

Q96AC1 Human, Q8CIB5 Mouse,

Cellular Locus

Cytoplasm, Nucleus, Cell surface.

Host

Mouse

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within human Kindlin 2 aa 301-350 / 680.

Isotype

IgG2a

Clone

A10G12

Conjugation

Non-conjugated

Type

Mouse monoclonal Antibody

Applications

WB, IF-Cell, IP

Positive Control

MDA-MB-231 cell lysate, Saos-2 cell lysate, mouse heart tissue lysate, mouse lung tissue lysate, rat heart tissue lysate, rat lung tissue lysate, MDA-MB-231.

Concentration

1 mg/mL

Dilution

WB: 1:1,000 ;IF-Cell: 1:100 ;IP: 1-2μg/sample

Purity

Protein A affinity purified.

Form

Liquid

Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 78 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No

Price

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