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Telomerase-IN-8

Telomerase-IN-8 is an orally active telomerase inhibitor with an IC50 value of 0.98 μM. It demonstrates substantial antiproliferative activity against various tumor cell lines, including PC3, Bcap-37, MGC-803, and HepG2. In xenograft mouse models with S180 sarcoma or HepG2 liver cancer, Telomerase-IN-8 exhibits notable antitumor effects. This compound is applicable for research in telomerase-targeted cancer therapy.

Product Specifications

CAS Number

1884341-01-8

Smiles

O=C1OC=2C=CC=CC2C=C1C3=NN (C (=O) CN (CCCC) CCCC) C (C=4C=CC=CC4) C3

Molecular Formula

C28H33N3O3

Molecular Weight

459.59

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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