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M-PEG-NHS ester (MW 10000)

M-PEG-NHS ester (MW 10000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

CAS Number

92451-01-9

Product Name Alternative

MPEG-SC (MW 10000) ; mPEG-Succinimidyl ester (MW 10000)

UNSPSC

12352200

Hazard Statement

H302, H315, H319

Target

PROTAC Linkers

Type

Biochemical Assay Reagents

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/m-peg-nhs-ester-mw-10000.html

Purity

98.0

Solubility

10 mM in DMSO

Smiles

COCCOCC(ON1C(CCC1=O)=O)=O.[n]

Molecular Formula

(C2H4O) nC7H9NO5

Molecular Weight

10000 (Average)

Precautions

H302, H315, H319

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Biochemical Assay Reagents

Clinical Information

No Development Reported

Isoform

Alkyl/ether Linkers; PEG Linkers

Available Sizes

Frequently Asked Questions

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