JAK1/TYK2-IN-5
JAK1/TYK2-IN-5 (compound A1) is an inhibitor of JAK1 and TYK2, exhibiting Ki values of 0.0044 nM for TYK2JH2, 0.02 nM for JAK1 JH2, 6.9 μM for JAK1 JH1, 0.79 μM for JAK2 JH1, 0.21 μM for JAK3 JH1, and 0.55 μM for TYK2JH1. Additionally, it inhibits STAT activation mediated by TYK2/JAK1, induced by IFNα.
Product Specifications
CAS Number
3026367-07-4
Smiles
O=C (N) C1=NN=C (C=C1NC2=CC=CC (C3=NN (C (=C3) P (=O) (C4CC4) C5CC5) C) =C2OC) NC (=O) C6CC6
Molecular Formula
C26H30N7O4P
Molecular Weight
535.55
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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